The AMA is calling a “national health crisis”-a severe shortage of medicines. Shortfalls of some 250 lifesaving generic drugs, mostly injectable meds used continually throughout ERS, ICU’s and cancer wards all over America. An estimated 90% of the nation’s anesthesiologists say they’re experiencing shortages. A reported 500,000 cancer patients have been unable to get drugs they need. Responders have been forced to use expired meds and even go without critical drug supplies for accident victims.
Drug shortages have increased about 27% in 2010 and again in 2011—re Univ of Utah hospitals and clinics.
Past two to three years we’ve seen unprecedented number of different types and different classes that have been unavailable. Tom Carey
Of America’s five largest manufacturers of generic injectable drugs—four were effectively forced to simultaneously take significant production offline in order to deal with FDA warnings. Their production declined by 30%. Forbes
Nine patients died from contaminated IV fluid in Alabama when they typical supply was unavailable—Reuters
Pediatric oncologist, know how to cure 70-80% of patients. But without the scarce cancer drugs you are out of business. DR. MIKE Link
The AHA says that 95% of the 820 community hospitals that responded to the groups
June 2011 survey reported experiencing at least one drug shortage in the past 6 months. A full 44% reported shortages of 21 or more different drugs. Some 47% of hospitals reported experiencing a shortage of at least one drug on a daily basis—Katherine Hobson
Unavailability of succinylcholine has led to adverse patient outcomes—sometimes even death. Arnold Berry.
The most common shortages are generic injectables such as propofol—epinephrine, heparin and even morphine. Hospital and health network magazine.
Regrettably most institutions have had to institute a review board often with involvement of their institutional ethics committee to develop harrowing plans of how to ration chemotherapy drugs. Dr Michelle Hudspeth
Doctors at the john Hopkins cancer center are rationing cytarabine a drug used to treat leukemia and lymphoma. They are literally deciding who will live and who will die. John Goodman.
Reuters reports that 58% of the 219 drugs on the shortage list were produced by facilities forced to shut down by the FDA but more were tied to reports of the drugs actually harming people.
Under Obama FDA commission Hamburg , the total number of FDA warning letters shot up to 1,720 in 2011 compared to 445 in 2008. FDA contribution to the drug shortage.
Heavy handed FDA inspections are throwing the nation’s drug suypply into disarray. Four of the five top generic drug makers Hospira, Teva Pharmaceuticals, Sandoz and Bedford Lab, were forced to shut down 30% of their manufacturing capacity by the FDA—-FDA contribution
FDA complained about the production quality of methotrexate—they only treatment for children with certain kinds of leukemia. The FDA tried to force Ben Venue Labs in Ohio to do expensive upgrade in the facility and the company shut down in Nov 2011—the sole US manufacturer of Doxil used in ovarian cancer. Latest Drug shortage threatens children
Hamburg’s aggressive enforcement and the fact that many generic mfg are actually losing money by producing certain drugs particularly for the elderly has led to production line being shut down and even shuttered mfg plants. More that 90% of US oncologist have experienced shortage of key cancer drugs. Reuters
We are finding that scores of critical drugs are now unavailable to people who need them. The first place to look when product shortages persist is for the presence of government price controls—Darrell Issa
Food and drug adm rules cause pointless delays. It takes as long a two and half years to receive FDA mfg approval for a generic. WSJ
11% of shortages were due to companies that stopped making a certain drug, usually for business reasons. Reuters
In some cases the drug shortage has created a gray market where things that used to cost $10 now cost $100. Hospitals and health network
To supposedly “fix” the problem on 10/31/2011, Obama signed an Exec Order instructing the FDA to speed up reviews for drug mfg and set up a voluntary advance warning system for potential shortages.
Still the FDA’s Sandra Kweder claims that Obama’s EO has helped the agency avert 150 new shortages since Nov. guess we should be happy it wasn’t the full 400.
Source—see above and limbaugh